AS3MT, arsenite methyltransferase, 57412

N. diseases: 56; N. variants: 18
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3740390
rs3740390
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0023487
Disease:
Acute Promyelocytic Leukemia 		0.010 GeneticVariation BEFREE These results indicate that inherent genetic information of the AS3MT rs3740390 genotypes is a novel predicted or evaluated target for As2O3-induced side effects and therapeutic efficacy for the treatment of APL. 30376134 2018
dbSNP: rs11191439
rs11191439
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0037284
Disease:
Skin lesion 		0.010 GeneticVariation BEFREE These findings indicate that Met287Thr influences the susceptibility to premalignant As skin lesions and might be at increased risk for other adverse health effects of iAs exposure. 19538983 2009
dbSNP: rs11191439
rs11191439
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0032927
Disease:
Precancerous Conditions 		0.010 GeneticVariation BEFREE These findings indicate that Met287Thr influences the susceptibility to premalignant As skin lesions and might be at increased risk for other adverse health effects of iAs exposure. 19538983 2009
dbSNP: rs11191454
rs11191454
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0004352
Disease:
Autistic Disorder 		0.010 GeneticVariation BEFREE Therefore, this family-based association study was performed in 640 Chinese Han autism trios to investigate the association between autism and 7 SNPs with genome-wide significance in previous GWAS (rs4307059 near MSNP1AS, rs4141463 in MACROD2, rs2535629 in ITIH3, rs11191454 in AS3MT, rs1625579 in MIR137HG, rs11191580 in NT5C2, and rs1409313 in CUEDC2). 30610940 2019
dbSNP: rs11191454
rs11191454
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs11191454
rs11191454
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0699885
Disease:
Carcinoma of bladder 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs11191454
rs11191454
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005695
Disease:
Bladder Neoplasm 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs3740393
rs3740393
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0699885
Disease:
Carcinoma of bladder 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs3740393
rs3740393
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs3740393
rs3740393
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0005695
Disease:
Bladder Neoplasm 		0.010 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs1046778
rs1046778
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0699885
Disease:
Carcinoma of bladder 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs1046778
rs1046778
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs1046778
rs1046778
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005695
Disease:
Bladder Neoplasm 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005695
Disease:
Bladder Neoplasm 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0699885
Disease:
Carcinoma of bladder 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.020 GeneticVariation BEFREE The polymorphisms of AS3MT rs11191438, AS3MT rs10748835, and AS3MT rs1046778 were related to the risk of BC and UTUC, while the polymorphisms of AS3MT rs3740393, AS3MT rs11191453, and AS3MT rs11191454 were associated with arsenic methylation capacity. 29859237 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0020473
Disease:
Hyperlipidemia 		0.010 GeneticVariation BEFREE The current study was to determine if coronary heart disease, hypertension, and hyperlipidemia were associated with low-level arsenic exposure and AS3MT gene single nucleotide polymorphism (SNP) A35991G (rs10748835) in rural Texas. 22341486 2012
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder 		0.020 GeneticVariation BEFREE The combination of AS3MT haplotype 2 (AS3MT rs11191453, rs11191454, rs10748835, and rs1046778)'s high-risk haplotype (C-G-A-C, T-A-A-C, and T-G-G-T) was significantly associated with increased risk of BC. 29669044 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0005695
Disease:
Bladder Neoplasm 		0.020 GeneticVariation BEFREE The combination of AS3MT haplotype 2 (AS3MT rs11191453, rs11191454, rs10748835, and rs1046778)'s high-risk haplotype (C-G-A-C, T-A-A-C, and T-G-G-T) was significantly associated with increased risk of BC. 29669044 2018
dbSNP: rs10748835
rs10748835
Entrez Id: 57412;100528007;107984265
Gene Symbol: AS3MT;BORCS7-ASMT;LOC107984265
AS3MT;BORCS7-ASMT;LOC107984265
CUI: C0699885
Disease:
Carcinoma of bladder 		0.020 GeneticVariation BEFREE The combination of AS3MT haplotype 2 (AS3MT rs11191453, rs11191454, rs10748835, and rs1046778)'s high-risk haplotype (C-G-A-C, T-A-A-C, and T-G-G-T) was significantly associated with increased risk of BC. 29669044 2018
dbSNP: rs3740393
rs3740393
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE The change in MMA% was linked to individual cancer susceptibility related to AS3MT rs3740393. 19680750 2009
dbSNP: rs3740393
rs3740393
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE The change in MMA% was linked to individual cancer susceptibility related to AS3MT rs3740393. 19680750 2009
dbSNP: rs7085104
rs7085104
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0206161
Disease:
Reticulocyte count (procedure) 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12764899
rs12764899
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019
dbSNP: rs12764899
rs12764899
Entrez Id: 57412;100528007
Gene Symbol: AS3MT;BORCS7-ASMT
AS3MT;BORCS7-ASMT
CUI: C0036341
Disease:
Schizophrenia 		0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203 2019